WebAssay development and high-throughput screening for small molecule inhibitors of a Vibrio cholerae stress response pathway Laura Stanbery, Jyl S Matson Department of Medical Microbiology and Immunology, College of Medicine and Life Sciences, The University of Toledo, Toledo, OH, USA Abstract: Antibiotics are important adjuncts to oral rehydration … WebMar 1, 2024 · High-throughput screening Enzyme assay Thermal shift assay Allosteric inhibitors Abbreviations AKT protein kinase B ALK anaplastic lymphoma kinase AML acute myelogenous leukemia Bis-tris bis- (2-hydroxyethyl)amino-tris (hydroxymethyl)methane BTLA B and T lymphocyte attenuator DiFMUP 6,8-difluoro-4-methylumbelliferyl phosphate …
High-Throughput Screening for the Discovery of Enzyme …
WebDec 17, 2024 · In this study, we developed a chemiluminescence-based high-throughput screening (HTS) assay for the discovery of human adenovirus 5 (HAdV5) antiviral … WebSep 14, 2009 · Selective lowering of amyloid-β levels with small-molecule γ-secretase inhibitors is a promising therapeutic approach for Alzheimer’s disease. In this work, we developed a high throughput assay for screening of γ-secretase inhibitors with endogenous γ-secretase and a fluorogenic substrate. The IC50 values of known γ-secretase inhibitors … dangers of investing in the stock market
Small-molecule high-throughput screening identifies a MEK inhibitor …
WebZika virus (ZIKV) pandemic and its implication in congenital malformations and severe neurological disorders had created serious threats to global health. ZIKV is a mosquito … WebOct 13, 2024 · We demonstrate the utility of this biosensor for inhibitor discovery by screening 1280 compounds from the Library of Pharmaceutically Active Compounds … WebOct 8, 2024 · High-Throughput Screening for the Discovery of Enzyme Inhibitors. Enzymes are common targets in high-throughput screening and related campaigns. An analysis of … birmingham to nuremberg