WebDedifferentiation and transdifferentiation are rare and only poorly understood phenomena in cutaneous melanoma. To study this disease more comprehensively we have retrieved 11 primary cutaneous melanomas from our pathology archives showing biphasic features characterized by a conventional melanoma and additional areas of de-/trans … Web3 feb. 2024 · SOX10 and Melan-A staining highlighted melanoma metastases in all cases but one. In that particular case, both SOX10 and Melan-A were negative, and they were also both negative in the primary melanoma. Additional IHC performed showed that the tumour was negative for S100, MSA, AE1/3 and CD45 as well.
阴道恶性肿瘤诊断与治疗指南(2024年版)_参考网
Web31 jul. 2024 · Schwannomas and neurofibromas diffusely express S-100 and SOX10, and perineuromas are positive for EMA, Glut-1, and claudin-1. Perivascular epithelioid cell neoplasms (PEComas) are exceedingly rare in the GI tract, consist of a mixture of epithelioid and spindle cells, and can be recognized by the coexpression of melanocytic (HMB-45, … Web6 mrt. 2024 · Immunocytochemical stains for S100, Melan-A, SOX10, HMB45 and PRAME were performed in 48 cytological samples of melanoma metastases. S100 and SOX10 were positive in all cases (100%). Melan-A, HMB45 and PRAME were negative in 1 (2.1%), 5 (10.4%) and 7 (14.6%) cases, respectively. luther college patrick whitesell
Jejunal Intussusception Secondary to a Large Inflammatory Fibroid …
WebPurpose: An immunohistochemical panel of S100 protein, Melan A and HMB-45 is commonly used to confirm the diagnosis of malignant melanoma due to the lack of … WebThis mutation has also been reported in colorectal, lung, and urinary carcinomas and cancer cell lines at a very low frequency. 5,11,12 The lack of cytokeratin staining and strong positivity for three melanoma markers (SOX10, HMB45, and melan A), in addition to the morphology, provided convincing evidence that the lesion examined was a malignant … Web11 sep. 2024 · SOX10 has been described as an additional marker for melanoma. However, comprehensive large-scale data about the expression of melanoma markers in NSCLC … luther college philosophy courses