Toppits trial

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August undefined, 2024

WebIn response, Watson et al completed a double blinded RCT (TOPPITS trial)1 2 looking into the effectiveness of PPIs for the treatment of throat symptoms and suspected LPR. Its comparison of Lansoprazole versus placebo did not show any significant difference in outcome and therefore has called into question conventional wisdom on how to manage ... WebJan 7, 2024 · In total, 265 of 346 (77%) participants had information on returned trial drug, of whom 262 (99%) were reported to have started treatment, taking at least one capsule. Of …

Histogram of time between randomisation and the 16-week

WebJul 30, 2024 · The ongoing Trial of Proton Pump Inhibitors in Throat Symptoms ( TOPPITS ), which is a UK-based, multi-centre, randomised, double-blinded, placebo-controlled trial of lansoprazole in patients with persistent throat symptoms attributable to LPR [ 20 ], aims to provide more robust information on the role of PPIs in treating LPR symptoms. WebWhen there were two ratings and confidence in the identified trial number, the chronologically first rating was used throughout. In all, 363 assessments had both a validated identifier and a RFS. Of these, 107 were duplicates, leaving 256 unique identifiable RFS assessments. chicken pox adults contagious

Lansoprazole for persistent throat symptoms in secondary care: …

WebTOPPITS: Trial Of Proton Pump Inhibitors in Throat Symptoms. Study protocol for a randomised controlled trial. Lookup NU author(s): Gillian Watson ORCiD, James O'Hara … WebA randomised, placebo controlled trial of extra-oesophageal reflux treatment in the management of upper respiratory symptoms. [TOPPITS: Trial of Proton Pump Inhibitors in Throat Symptoms] Trial Information Subject Disposition Baseline Characteristics End Points Adverse Events More Information Collapse all Expand all WebTOPPITS: Trial Of Proton Pump Inhibitors in Throat Symptoms. Study protocol for a randomised controlled trial Article Full-text available Apr 2016 TRIALS Gillian C Watson James O'Hara Paul... chicken pox adults contagious period

EudraCT Number 2013-004249-17 - Clinical trial results

PRIME PubMed TOPPITS: Trial Of Proton Pump Inhibitors in …

WebTOPPITS Trial of Proton Pump Inhibitors in Throat Symptoms • Study Stage: Closed • Sponsor: The Newcastle upon Tyne Hospitals NHS Foundation Trust • Funder: NIHR HTA • … WebTOPPITS: Trial Of Proton Pump Inhibitors in Throat Symptoms. Study protocol for a randomised controlled trial. Trials 2016; 17:175. DOI. Jagger C, Matthews FE, Wohland P, Fouweather T, Stephan BCM, Robinson L, Arthur A, Brayne C (2016). goonhammer disciples of tzeentchWebTOPPITS: Trial Of Proton Pump Inhibitors in Throat Symptoms. Study protocol for a randomised controlled trial. Article. Full-text available. Apr 2016; Gillian C Watson; James O’Hara; goonhammer deathwatch

"WebApr 1, 2016 · TOPPITS: Trial Of Proton Pump Inhibitors in Throat Symptoms. Study protocol for a randomised controlled trial. " - Toppits trial

Toppits trial

WebThe Trial Of Proton Pump Inhibitors in Throat Symptoms (TOPPITS) aimed to detect clinically relevant difference with 90% power. The 346 randomised participants reduced to … WebTOPPITS: Trial Of Proton Pump Inhibitors in Throat Symptoms. Study protocol for a randomised controlled trial. KOL Key Opinion Leaders & Influencers . Conditions. close . …

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WebTrial Of Proton Pump Inhibitors in Throat Symptoms (TOPPITS) addresses the problem of adults with persistent throat symptoms such as globus, catarrh, throat discomfort, … WebTOPPITS: Trial Of Proton Pump Inhibitors in Throat Symptoms. Study protocol for a randomised controlled trial. Watson G, O'Hara J, Carding P, Lecouturier J, Stocken D, Fouweather T, Wilson J Trials 2016 Apr 1;17:175. doi: 10.1186/s13063-016-1267-7.

WebThe Trial Of Proton Pump Inhibitors in Throat Symptoms (TOPPITS) aimed to detect clinically relevant difference with 90% power. The 346 randomised participants reduced to 283 at the primary end point; 267 completed the primary outcome measure, 220 within the protocol time scale. WebThis trial was an investigator initiated, multicentre, randomised, double blind, placebo controlled trial conducted in eight hospitals in the UK. The trial protocol was approved by …

WebOct 9, 2014 · A further study not registered at the time of searching, the Trial of Proton Pump Inhibitors in Throat Symptoms (TOPPITS) is under way (UKCRN ID 16317). It is a multicentre, randomised, double blind, placebo controlled trial of lansoprazole in patients with persistent throat symptoms, using three patient reported outcome measures for … WebApr 1, 2016 · TOPPITS is designed to evaluate the relative effectiveness of treatment with a proton pump inhibitor versus placebo in patients with persistent throat symptoms to …

WebThe TOPPITS outcome stands to contribute to future throat symptom guidance, particularly given the current popularity for primary PPI treatment. The TOPPITS results provide …

WebTOPPITS was an investigator-initiated multicentre, randomised, double-blind, placebo controlled trial conducted in eight hospitals in the UK. 9 The full trial methodology has been published... chicken pox adults nice cksWebTOPPITS: Trial Of Proton Pump Inhibitors in Throat Symptoms. Study protocol for a randomised controlled trial. BMC Trials 2016, 17, 175. Rubie IEM, Haighton CA, O'Hara J, Rousseau NS, Steen IN, Stocken DD, Sullivan F, Vale L, Wilkes S, Wilson JA. chickenpox adults nice cksWebTOPPITS was an investigator-initiated multicentre, randomised, double-blind, placebo controlled trial conducted in eight hospitals in the UK. 9 The full trial methodology has been published previously. 10 This study was authorised by the TOPPITS Trials Steering Committee (TSC). Participants and presenting characteristics chicken pox adults symptomsWebMETHODS A pragmatic randomized controlled trial with a mixed-methods design in patients aged 18 to 80 years with 3 or more chronic conditions from 7 family medic... Managing pain in HIV/AIDS: a... goonhammer emperor\\u0027s childrenWebPhase three randomised trial comparing invasive and conservative treatment strategies in older patients with non-ST elevation myocardial infarction. SETS aHUS. Multicentre, open label, prospective, single arm study of the safety and impact of eculizumab withdrawal in patients with atypical haemolytic uraemic syndrome ... TOPPITS. Trial of ... goonhammer expanding age of darknessWebIn total, 262 out of 346 trial participants (76%) are assumed to have taken at least one capsule of their trial medication and are included in the per-treatment analysis group [126 out of 172 (73%) in the lansoprazole group; 136 out of 174 (78%) in the placebo group]. Further details of dose taken are given in Appendix 2, Table 38. chicken pox adults second timeWebTOPPITS is designed to evaluate the relative effectiveness of treatment with a proton pump inhibitor versus placebo in patients with persistent throat symptoms. This will provide … chicken pox adults nice